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Do
you know serious drug Interaction with Yasmin and YAZ birth control pills?
Yasmin
and YAZ birth control pills are widely popular oral contraceptive brands for giving
maximum protection against unintended pregnancies but they may create serious
side effects due to drug-drug interaction
Yasmin
and Yaz are two most popular brands of
birth control pills in U.S.A. Both are combined oral contraceptive pills, which
contain special progestin hormone called drospirenone, which is not found in other
combined pills. Both the pills contain two main hormones: drospirenone and ethinyl
estradiol, which protect against pregnancy upto 99% if taken as directed.
In
a recent report published in the well-known contraception journal, physicians
have stressed that some of the medicines that used to raise potassium may interact
with birth control pills containing drospirenone and ethinyl estradiol, which
very much present in Yasmin and Yaz. It is so because both these pills may increase
potassium level and interaction with medicines, which are also responsible for
raising potassium level, may cause highest potassium level at the alarming level.
Potassium retention is found in the medicines that are recommended for high blood
pressure, treatment for heart problems, anti-inflammatory medicines (like Ibuprofen).
Similarly, this level could also be found in "water retention" types of pills
like diuretics.
Now, both Yasmin and Yaz birth control pills
come with product label instruction for physicians and healthcare providers recommending
these products to monitor the serum potassium levels in the first month for those
patients who are also under treatment with other potassium retention drugs.
It
has been found that 18% of women were taking Yasmin birth control pills alongwith
other potassium retaining drug, surprisingly, this 30% of such cases happened
in the first month of the Yasmin birth control pills dosage. Family practice or
physicians or OB/GYN prescribes almost 18% of women who are taking Yasmin with
other potassium retaining medicines at the same time.
What
drug(s) may interact with drospirenone; ethinyl estradiol?
1. anastrozole
2.
antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine,
and griseofulvin 3. aprepitant, a medicine used for chemotherapy-induced nausea
and vomiting
4. barbiturate medicines for producing sleep or treating seizures
(convulsions)
5. bosentan
6. carbamazepine
7. caffeine
8. clofibrate
9. cyclosporine
10. dantrolene
11. doxercalciferol
12. exemestane
13. grapefruit juice
14. hydrocortisone
15. letrozole
16. medicines
for anxiety or sleeping problems, such as diazepam or temazepam
17. medicines
for mental depression
18. medicines for diabetes, including troglitazone and
pioglitazone
19. mineral oil
20. modafinil
21. mycophenolate
22.
nefazodone
23. oxcarbazepine
24. phenytoin
25. prednisolone
26.
ritonavir or other medicines for HIV infection or AIDS
27. selegiline
28.
soy isoflavones supplements
29. St. John's wort
30. tamoxifen or raloxifene
31. testolactone
32. theophylline
33. topiramate
34. warfarin
Drugs that can increase your potassium level include:
- certain
medications for high blood pressure or heart conditions (examples include ACE-inhibitors
like Altace®, Capoten®, Lotensin®, Mavik®, Monopril®, Prinivil®, Univasc®, Vasotec®,
Zestril®, and also Angiotensin-II receptor blockers like Atacand®, Avapro®, Cozaar®,
Diovan®, Micardis®), as well as Eplerenone (Inspra™)
- dietary salt substitutes
(these may contain potassium)
- heparin
- NSAIDs (antiinflammatory
drugs which include Advil®, Aleve®, Ansaid®, Cataflam®, Clinoril®, Daypro®, Feldene®,
Indocin®, Lodine®, Naprosyn®, Orudis®, Motrin®, Voltaren®, and others) if they
are taken long-term and daily, like for arthritis
- potassium supplements
- some
'water pills' (diuretics like spironolactone or Aldactone®, Dyazide®, Midamor®,
Moduretic®, and others)
Since the Yasmin and YAZ
are two popular brands among women and if you are planning to go for either of
them for your contraception needs, please inform your physician or healthcare
provider if you were on any other type of medicine, specially those described
above potassium raising drugs.
Linda Crowford is an author
for many successful articles and ebooks written on women's health, birth
control pills, birth
control birth control, pregnancy issues and human relationship. Please visit
the site http://www.mybirthcontrolstore.com to know various birth control pills,
birth control methods and options are available for today's women.